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Table 1 Features of recent studies of glucose control in intensive care units

From: Tight blood glucose control: a recommendation applicable to any critically ill patient?

  Reference
  [2] [4] [5] [7]
Design Prospective, interventional Retrospective, observational Retrospective, observational Retrospective, observational
Target glucose levels (mmol/l)
   Intervention 4.4–6.1 <8.0 4.4–7.8  
   Control 10.0–11.1 Not available 10.0–11.1 >12.0
Types of admission (n)
   Surgical 1548 462 573 160
   Medical 0 61 1027 0
Cardiac surgery (% of total) 63 85 0 0
Median APACHE II score 9 16 16 Not available
ICU mortality (%)
   Intervention 4.6 Not available 14.8 3.3
   Control 8.0   20.9  
Primary end-points ICU mortality ICU mortality ICU mortality Infection rate, length of hospital stay
Secondary end-points In-hospital mortality, organ dysfunction, tranfusion rate, critical illness polyneuropathy, infection rate   Organ dysfunction, transfusion rate, length of ICU stay, infection rate  
  1. APACHE, Acute Physiology and Chronic Health Evaluation; ICU, intensive care unit.