Table 1 Features of recent studies of glucose control in intensive care units
From: Tight blood glucose control: a recommendation applicable to any critically ill patient?
| Â | Reference | |||
|---|---|---|---|---|
| Â | [2] | [4] | [5] | [7] |
Design | Prospective, interventional | Retrospective, observational | Retrospective, observational | Retrospective, observational |
Target glucose levels (mmol/l) | ||||
   Intervention | 4.4–6.1 | <8.0 | 4.4–7.8 |  |
   Control | 10.0–11.1 | Not available | 10.0–11.1 | >12.0 |
Types of admission (n) | ||||
   Surgical | 1548 | 462 | 573 | 160 |
   Medical | 0 | 61 | 1027 | 0 |
Cardiac surgery (% of total) | 63 | 85 | 0 | 0 |
Median APACHE II score | 9 | 16 | 16 | Not available |
ICU mortality (%) | ||||
   Intervention | 4.6 | Not available | 14.8 | 3.3 |
   Control | 8.0 |  | 20.9 |  |
Primary end-points | ICU mortality | ICU mortality | ICU mortality | Infection rate, length of hospital stay |
Secondary end-points | In-hospital mortality, organ dysfunction, tranfusion rate, critical illness polyneuropathy, infection rate | Â | Organ dysfunction, transfusion rate, length of ICU stay, infection rate | Â |