The effect of interruption to propofol sedation on auditory event-related potentials and electroencephalogram in intensive care patients

Yppärilä, Heidi; Nunes, Silvia; Korhonen, Ilkka; Partanen, Juhani; Ruokonen, Esko

doi:10.1186/cc2984

Critical Care

Table 1 Demographic data, duration and rate of propofol infusion at the time of measurements

From: The effect of interruption to propofol sedation on auditory event-related potentials and electroencephalogram in intensive care patients

Patient number/sex	Age (years)	Length (cm)	Weight (kg)	Diagnosis	Propofol infusion^a (mg/kg per hour)	Duration of infusion^b (hours)	Opioids^c
1/M	59	180	86	Thoracic aorta dissection	1.63	31	Oxycodon 10 mg
2/M	53	180	130	Acute myocardial infarction	0.62	11	Fentanyl 0.100 mg/hour
3/M	47	173	68	Pneumonia and sepsis (streptococcal pneumonia)	1.18	13	Oxycodon 3 mg
4/F	47	170	68	Multitrauma (renal rupture, pelvic fracture)	1.76	20	Oxycodon 10 mg
5/M	61	169	96	Ruptured abdominal aortic aneurysm	2.08	19	Fentanyl 0.100 mg/hour
6/M	76	174	73	Acute myocardial infarction and peritonitis	2.47	66	Fentanyl 0.100 mg/hour
7/F	72	160	70	Acute lung injury and status post-AVR+CABG	1.71	10	Oxycodon 5 mg
8/M	66	176	90	Acute lung injury and status post-CABG	4.44	46	Fentanyl 0.150 mg/hour
9/M	68	162	79	Wound infection post-CABG	3.04	112	Oxycodon 35 mg
10/M	64	164	65	Peritonitis and septic shock	1.85	13	Fentanyl 0.200 mg
11/F	70	162	89	Acute myocarial infarction and status post-CABG	0.67	16	Oxacodon 5 mg
12/M	83	167	65	Peritonitis	2.15	19	Fentanyl 0.075 mg
13/M	72	176	96	Sternal dehiscence post-CABG	1.46	14	Oxycodon 36 mg
14/M	76	183	77	Acute myocarial infarction and pulmonary haemorrhage	1.04	18	Oxycodon 10 mg
15/F	71	162	58	Wound infection post-CABG+AVR	1.72	19	Fentanyl 0.150 mg, oxycodon 29 mg
16/M	77	167	73	Acute respiratory distress syndrome	2.74	69	Fentanyl 0.825 mg, oxycodon 15 mg
17/F	50	170	75	Low cardiac output (status post-CABG)	1.60	86	Fentanyl 0.150 mg/hour
18/F	59	165	60	Acute lung injury and septic shock	1.67	12	Oxycodon 3 mg
19/M	71	170	80	Acute myocarial infarction and pulmonary oedema	1.50	14	Oxycodon 18 mg
Mean	65	170	79	-	1.91	31	-
SD	11	7	16	-	0.88	29	-

^aRate of propofol infusion at the time of measurements. ^bNumber of hours of continuous propofol infusion before measurements. ^cOpioid medication administered during the 12 hours before (total intravenous bolus) and/or during the measurements (infusion rate). AVR, aortic valve replacement; CABG, coronary artery bypass graft.

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ISSN: 1364-8535

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