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Table 4 Numbers of lambs undergoing various resuscitative measures

From: Cardiovascular stability during arteriovenous extracorporeal therapy: a randomized controlled study in lambs with acute lung injury

Type of support

Group

P a

 

CMV (n = 8)

AV-ECMO (n = 9)

 

Lactated Ringer's (10 ml/kg)

2

8

0.015

Epinephrine (0.5–2 μg/kg per min)

1

6

0.049

Dopamine (5 μg/kg per min)

1

6

0.049

Bicarbonate (1 mEq/kg bolus)

1

6

0.049

Surviving/nonsurviving

6/2

4/5

0.333

Total number of resuscitative measures in surviving lambs

2 (n = 6)

12 (n = 4)

0.001

Cause of death

Prolonged hypotension with MAP <30 mmHg

Prolonged hypotension with MAP <30 mmHg and AV shunt <5% of CO

 
  1. Comparison of various resuscitative measures after acute lung injury in surviving and nonsurviving lambs subjected to conventional mechanical ventilation (CMV) with closed arteriovenous (AV) shunt or CMV with AV-extracorporeal membrane oxygenation (ECMO) using up to 15% AV shunt. aP values derived using Fisher's exact test. CO, cardfiac output; MAP, mean arterial pressure.