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Table 3 Gas exchage variables

From: Cardiovascular stability during arteriovenous extracorporeal therapy: a randomized controlled study in lambs with acute lung injury

  Study period (hours after establishment of acute lung injury)
Variable 0 (baseline) 2 4 6
PaO2 (mmHg)     
   CMV 131 ± 90 207 ± 171 231 ± 175 221 ± 189
   AV-ECMO 174 ± 100 95 ± 29 77 ± 17* 94 ± 76
PaCO2 (mmHg)     
   CMV 41.3 ± 3.1 43.4 ± 8.3 38.9 ± 10.3 37.0 ± 7.1
   AV-ECMO 34.8 ± 2.3** 35.1 ± 8.5 37.1 ± 7.8 37.8 ± 5.7
pH     
   CMV 7.263 ± 0.05 7.237 ± 0.05 7.286 ± 0.10 7.289 ± 0.08
   AV-ECMO 7.322 ± 0.04* 7.277 ± 0.15 7.235 ± 0.10 7.207 ± 0.14
HCO3- (mmol/l)     
   CMV 17.0 ± 3.1 16.8 ± 3.2 16.7 ± 2.7 15.9 ± 3.3
   AV-ECMO 17.2 ± 2.4 15.7 ± 2.3 15.7 ± 5.4 14.6 ± 4.6
Arterial Hb-O2 (%)     
   CMV 91.8 ± 8.1 89.2 ± 14.9 94.0 ± 4.9 88.9 ± 18.4
   AV-ECMO 90.7 ± 16.5 89.0 ± 9.9 84.4 ± 7.0 74.0 ± 24.8
O2 extraction (%)     
   CMV 42.4 ± 15.6 37.6 ± 9.2 47.2 ± 11.5 41.2 ± 6.9
   AV-ECMO 41.6 ± 11.9 37.3 ± 14.2 49.3 ± 21.0 43.3 ± 21.7
  1. Gas exchage variables in lung injured lambs (surviving) supported by conventional mechanical ventilation (CMV; n = 6) or arteriovenous (AV)-extracorporeal membrane oxygenation (ECMO; n = 4) during a 6-hour period of study. No significant differences were found when comparing baselines (time 0) with 2, 4, and 6 hours of study by repeated measures analysis of variance (ANOVA) followed by Dunnett multiple comparisons test. Values are expressed as mean ± standard deviation. *P < 0.05, **P < 0.01, CMV versus AV-ECMO group; ANOVA followed by Bonferroni multiple comparisons test. Hb-O2, hemoglobin–oxygen saturation; PaCO2, arterial carbon dioxide tension; PaO2, arterial oxygen tension.