From: Science review: The use of proton pump inhibitors for gastric acid suppression in critical illness
Characteristic | Sucralfate | Antacids | H2RAs | Esomeprazole | Lansoprazole | Omeprazole | Pantoprazole | Rabeprazole |
---|---|---|---|---|---|---|---|---|
Efficacy in elevating gastric pH | Â | + | + | +++ | +++ | +++ | +++ | +++ |
Tolerability | + | + | + | +++ | +++ | +++ | +++ | +++ |
Use in organ failure | Â | Â | Â | Â | Â | Â | + | Â |
Low potential for drug interactions | Â | Â | Â | Â | Â | Â | + | Â |
Administration options | Â | Â | Â | Â | Â | Â | Â | Â |
   Oral |  |  |  | + | + | + | + | + |
   Intravenous |  |  | + | + |  | + | + |  |
   Nasogastric | + | + |  | + | + | + |  |  |