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Table 2 Gas exchange during acute lung injury in sheep

From: Extravascular lung water assessed by transpulmonary single thermodilution and postmortem gravimetry in sheep

Parameter Group Time point (hours)
   0 2 4 6
pHa Sham 7.52 ± 0.03 7.53 ± 0.02 7.50 ± 0.02 7.50 ± 0.02
  LPS 7.48 ± 0.01 7.50 ± 0.02 7.55 ± 0.02* 7.53 ± 0.02
  OA 7.50 ± 0.01 7.44 ± 0.03 - -
PaCO2 (mmHg) Sham 38.7 ± 2.7 36.4 ± 2.1 36.4 ± 1.6 37.4 ± 1.0
  LPS 39.7 ± 1.4 38.8 ± 1.5 32.6 ± 0.6* 33.1 ± 1.0*
  OA 36.4 ± 1.1 42.5 ± 3.7 - -
Haemoglobin (g/dl) Sham 10.7 ± 0.9 10.1 ± 0.6 10.2 ± 0.5 10.3 ± 0.5
  LPS 10.4 ± 0.6 10.4 ± 0.6 11.0 ± 0.7* 10.9 ± 0.6
  OA 10.3 ± 0.4 10.7 ± 0.5 - -
Blood temperature (°C) Sham 39.3 ± 0.1 39.2 ± 0.1 39.3 ± 0.1 39.3 ± 0.1
  LPS 39.3 ± 0.1 40.0 ± 0.1* 41.3 ± 0.1* 41.0 ± 0.1*
  OA 39.5 ± 0.1 39.6 ± 0.1 - -
  1. Data are expressed as means ± standard error of the mean. *P < 0.05, versus t = 0 hours in LPS group; P < 0.05, OA versus sham operated group; P < 0.05, LPS versus sham-operated group. LPS, lipopolysaccharide; OA, oleic acid; PaCO2, arterial carbon dioxide tension; Sham, sham-operated.