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Table 2 Gas exchange during acute lung injury in sheep

From: Extravascular lung water assessed by transpulmonary single thermodilution and postmortem gravimetry in sheep

Parameter

Group

Time point (hours)

  

0

2

4

6

pHa

Sham

7.52 ± 0.03

7.53 ± 0.02

7.50 ± 0.02

7.50 ± 0.02

 

LPS

7.48 ± 0.01

7.50 ± 0.02

7.55 ± 0.02*

7.53 ± 0.02

 

OA

7.50 ± 0.01

7.44 ± 0.03

-

-

PaCO2 (mmHg)

Sham

38.7 ± 2.7

36.4 ± 2.1

36.4 ± 1.6

37.4 ± 1.0

 

LPS

39.7 ± 1.4

38.8 ± 1.5

32.6 ± 0.6*

33.1 ± 1.0*

 

OA

36.4 ± 1.1

42.5 ± 3.7

-

-

Haemoglobin (g/dl)

Sham

10.7 ± 0.9

10.1 ± 0.6

10.2 ± 0.5

10.3 ± 0.5

 

LPS

10.4 ± 0.6

10.4 ± 0.6

11.0 ± 0.7*

10.9 ± 0.6

 

OA

10.3 ± 0.4

10.7 ± 0.5

-

-

Blood temperature (°C)

Sham

39.3 ± 0.1

39.2 ± 0.1

39.3 ± 0.1

39.3 ± 0.1

 

LPS

39.3 ± 0.1

40.0 ± 0.1*

41.3 ± 0.1*

41.0 ± 0.1*

 

OA

39.5 ± 0.1

39.6 ± 0.1

-

-

  1. Data are expressed as means ± standard error of the mean. *P < 0.05, versus t = 0 hours in LPS group; P < 0.05, OA versus sham operated group; P < 0.05, LPS versus sham-operated group. LPS, lipopolysaccharide; OA, oleic acid; PaCO2, arterial carbon dioxide tension; Sham, sham-operated.