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Table 5 Cytokine levels

From: Effects of lornoxicam on the physiology of severe sepsis

Cytokine Baseline Hours after the start of infusion
   24 48 72
TNF-α (pg/ml)     
Lornoxicam 25.7 ± 15 27.4 ± 16 26.68 ± 12.9 28.1 ± 16.8
Placebo 24.6 ± 18 25.4 ± 16.9 25.55 ± 11.8 26.3 ± 14.2
Il-1β (pg/ml)     
Lornoxicam 6.4 ± 3.8 6.48 ± 6.07 6.21 ± 3.26 6.57 ± 1.8
Placebo 6.35 ± 1.4 6.2 ± 4.30 6.34 ± 4.2 6.19 ± 2.7
IL-2 receptor (U/ml)     
Lornoxicam 1950 ± 1266 1890 ± 1150 1929 ± 1027 2050 ± 1100
Placebo 2270 ± 1110 2179 ± 1005 2300 ± 1190 2268 ± 1000
IL-6 (pg/ml)     
Lornoxicam 100.6 ± 58 105.2 ± 54 108.5 ± 47 104.8 ± 38
Placebo 114.5 ± 385 115.6 ± 48 113.6 ± 51 116 ± 28
IL-8 (pg/ml)     
Lornoxicam 171.50 ± 35 171.6 ± 19.3 172.1 ± 12.6 168.9 ± 11.3
Placebo 169.55 ± 27 168.3 ± 18.4 169.8 ± 18.2 171.0 ± 18.2
  1. No significant differences were found between groups. Data are expressed as mean ± standard deviation. IL, interleukin; TNF, tumour necrosis factor.