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Table 4 Biochemical parameters

From: Effects of lornoxicam on the physiology of severe sepsis

Parameter

Baseline

Hours after the start of infusion

  

24

48

72

Lactate (mg/dl)

    

Lornoxicam

25.2 ± 4.1

25.0 ± 3.9

25.9 ± 5.2

26.2 ± 3.7

Placebo

26.3 ± 3.8

26.7 ± 2.9

27.0 ± 3.1

26.9 ± 4.8

Platelets (×109/l)

    

Lornoxicam

192.9 ± 16.5

193.5 ± 15.0

178.1 ± 15.4

182.9 ± 15.6

Placebo

188.5 ± 14.4

190.8 ± 15.1

188.7 ± 13.3

190.5 ± 16.7

Leucocytes (×109/l)

    

Lornoxicam

14 ± 8.3

15.8 ± 8.3

16.0 ± 7.8

15.9 ± 6.2

Placebo

13.5 ± 6.6

14.7 ± 4.7

15.7 ± 6.7

14.8 ± 7.4

Bilirubin (mg/dl)

    

Lornoxicam

0.89 ± 0.38

0.90 ± 0.45

0.93 ± 0.33

0.90 ± 0.34

Placebo

0.90 ± 0.62

0.91 ± 0.38

0.92 ± 0.28

0.91 ± 0.36

Alanine aminotransferase (IU/l)

    

Lornoxicam

35.4 ± 5.5

36.0 ± 10.8

35.1 ± 8.6

36.7 ± 8.4

Placebo

35.4 ± 7.4

35.5 ± 5.2

36.2 ± 6.0

37.4 ± 4.9

Creatinine (mg/dl)

    

Lornoxicam

1.13 ± 0.96

1.15 ± 0.85

1.2 ± 0.3

1.28 ± 0.8

Placebo

1.01 ± 0.91

1.1 ± 0.65

1.08 ± 0.7

1.1 ± 0.8

  1. No significant differences were found between groups. Data are expressed as mean ± standard deviation.