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Table 3 Haemodynamic, oxygen and temperature variables

From: Effects of lornoxicam on the physiology of severe sepsis

Parameter Baseline Hours after the start of infusion
   24 48 72
Heart rate (beats/min)     
Lornoxicam 98 ± 24 99 ± 24 99 ± 22 96 ± 22
Placebo 95 ± 17 100 ± 23 98 ± 23 97 ± 22
Mean arterial pressure (mmHg)     
Lornoxicam 91 ± 16 92 ± 13 89 ± 13 93 ± 13
Placebo 91 ± 18 93 ± 14 91 ± 12 89 ± 11
Arterial pH     
Lornoxicam 7.34 ± 0.08 7.36 ± 0.07 7.33 ± 0.10 7.36 ± 0.06
Placebo 7.35 ± 0.07 7.37 ± 0.07 7.34 ± 0.07 7.37 ± 0.05
PaCO2 (torr)     
Lornoxicam 34.8 ± 12.1 34.6 ± 11.8 35.00 ± 9.2 36.54 ± 11.1
Placebo 32.6 ± 10 33.5 ± 10.2 36.3 ± 10.13 34.33 ± 12
PaO2/FiO2 ratio (torr)     
Lornoxicam 182 ± 68 186 ± 56 188 ± 64 189 ± 76
Placebo 184 ± 76 187 ± 45 181 ± 68 185 ± 68
SaO2 (%)     
Lornoxicam 96.1 ± 3 96.1 ± 3.1 95.9 ± 3.8 95.9 ± 4.2
Placebo 96.9 ± 3.1 96.0 ± 3.2 96.0 ± 2.8 95.8 ± 3.9
Temperature (°C)     
Lornoxicam 37.8 ± 0.75 37.2 ± 0.6 37.8 ± 0.5 37.9 ± 0.4
Placebo 37.6 ± 0.57 37.8 ± 0.4 37.6 ± 0.6 37.8 ± 0.5
  1. No significant differences were found between groups. Data are expressed as mean ± standard deviation. FiO2, fractional oxygen tension; PaCO2, arterial carbon dioxide tension; PaO2, arterial oxygen tension; SaO2, arterial oxygen saturation.