Table 3 Haemodynamic, oxygen and temperature variables
From: Effects of lornoxicam on the physiology of severe sepsis
Parameter | Baseline | Hours after the start of infusion | ||
|---|---|---|---|---|
24 | 48 | 72 | ||
Heart rate (beats/min) | ||||
Lornoxicam | 98 ± 24 | 99 ± 24 | 99 ± 22 | 96 ± 22 |
Placebo | 95 ± 17 | 100 ± 23 | 98 ± 23 | 97 ± 22 |
Mean arterial pressure (mmHg) | ||||
Lornoxicam | 91 ± 16 | 92 ± 13 | 89 ± 13 | 93 ± 13 |
Placebo | 91 ± 18 | 93 ± 14 | 91 ± 12 | 89 ± 11 |
Arterial pH | ||||
Lornoxicam | 7.34 ± 0.08 | 7.36 ± 0.07 | 7.33 ± 0.10 | 7.36 ± 0.06 |
Placebo | 7.35 ± 0.07 | 7.37 ± 0.07 | 7.34 ± 0.07 | 7.37 ± 0.05 |
PaCO2 (torr) | ||||
Lornoxicam | 34.8 ± 12.1 | 34.6 ± 11.8 | 35.00 ± 9.2 | 36.54 ± 11.1 |
Placebo | 32.6 ± 10 | 33.5 ± 10.2 | 36.3 ± 10.13 | 34.33 ± 12 |
PaO2/FiO2 ratio (torr) | ||||
Lornoxicam | 182 ± 68 | 186 ± 56 | 188 ± 64 | 189 ± 76 |
Placebo | 184 ± 76 | 187 ± 45 | 181 ± 68 | 185 ± 68 |
SaO2 (%) | ||||
Lornoxicam | 96.1 ± 3 | 96.1 ± 3.1 | 95.9 ± 3.8 | 95.9 ± 4.2 |
Placebo | 96.9 ± 3.1 | 96.0 ± 3.2 | 96.0 ± 2.8 | 95.8 ± 3.9 |
Temperature (°C) | ||||
Lornoxicam | 37.8 ± 0.75 | 37.2 ± 0.6 | 37.8 ± 0.5 | 37.9 ± 0.4 |
Placebo | 37.6 ± 0.57 | 37.8 ± 0.4 | 37.6 ± 0.6 | 37.8 ± 0.5 |