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Table 1 Sepsis-related (or Sequential) Organ Failure Assessment (SOFA) scores

From: Effects of lornoxicam on the physiology of severe sepsis

Parameter

SOFA score

 

0

1

2

3

4

Respiration (PaO2/FiO2 ratio)

>400

≤ 400

≤ 300

≤ 200 with respiratory support

≤ 100

Coagulation (platelets × 103/mm3

>150

≤ 150

≤ 100

≤ 50

≤ 20

Liver (bilirubin [mg/dl (μmol/l)])

<1.2 (<20)

1.2–1.9 (20–32)

2.0–5.9 (33–101)

6.0–11.9 (102–204)

>12.0 (>204)

Cardiovascular (hypotension)

No hypotension

MAP <70 mmHg

Dopamine ≤ 5 or dobutamine at any dose

Dopamine>5 or adrenaline (epinephrine) ≤ 0.1 noradrenaline (norepinephrine) ≤ 0.1

Dopamine >15 or adrenaline >0.1 noradrenaline >0.1

Central nervous system (GCS score)

15

19–14

10–12

6–9

<6

Renal (creatine [mg/dl] or urine output)

<1.2

1.2–1.9

2.0–3.4

3.5–4.9 or <500 ml/day

>5 or <200 ml/day

  1. FiO2, fractional inspired oxygen; GCS, Glasgow Coma Scale; MAP, mean arterial pressure;
  2. PaO2, arterial oxygen tension.