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Table 1 Summary of studies of dantrolene treatment of heat stroke in humans

From: Clinical review: Treatment of heat stroke: should dantrolene be considered?

   

Numbers included

   

Reference

Study type

Setting

Dantrolene treatment arms

Control arms

Dantrolene dose (mg/kg bw)

Improved parameters

Nonimproved parameters

[21]

Randomized, double-blind, controlled

Patients with classic heat stroke

26

26

2

-

Cooling rate, mean number of hospital stays

[17]

Randomized controlled

Heat stroke patient

8

12

2–4

Cooling rate

Survival, neurological sequelae

  1. bw, Body weight.
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Critical Care

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