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Table 2 Immune parameters at onset of infection, early and late septic shock

From: Altered immune parameters in chronic alcoholic patients at the onset of infection and of septic shock

Parameter

Chronic alcoholic patients

Nonalcoholic patients

P

IL-10 (pg/ml)

   Infection

35 (2–37)

41 (12–392)

0.110

   Early septic shock

37 (4–371)

66 (2–255)

0.590

   Late septic shock

30 (2–118)

35 (0–81)

0.576

Soluble TNF-RI (pg/ml)

   Infection

3440 (1280–6680)*

4750 (3540–7880)

0.153

   Early septic shock

10,860 (2260–16,670)*

7170 (3280–14,950)

0.622

   Late septic shock

9410 (1240–15,940)

7920 (4130–15,000)

0.775

Soluble TNF-RII (pg/ml)

   Infection

7280 (3990–8500)

7180 (5930–8890)

0.668

   Early septic shock

8070 (3500–8500)

7900 (5100–10,000)

0.895

   Late septic shock

7980 (3050–8500)

8120 (5480–10,660)

0.567

TNF-α (pg/ml)

   Infection

10 (4–18)

19 (12–93)

0.048

   Early septic shock

14 (1–56)

14 (3–29)

0.385

   Late septic shock

10 (1–29)

10 (7–16)

0.723

  1. Values are expressed as median (range). IL, interleukin; TNF, tumour necrosis factor; TNF-R, tumour necrosis factor receptor. *Significant changes from infection to early septic shock, and from early septic shock to late septic shock.