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Table 2 Respiratory, hemodynamic and tonometric measurements

From: Effects of positive end-expiratory pressure on gastric mucosal perfusion in acute respiratory distress syndrome

Parameter Baseline (n = 8) PEEP 10 (n = 8) PEEP 15 (n = 8) PEEP 20 (n = 7) Ideal PEEP (n = 7) P
PEEP (cmH2O) 9 (4–12) 10 15 20 12 (8–15)  
Mean airway pressure (cmH2O) 13.2 (8–18.7) 14 (12–17) 19 (17–22.2) 24 (22–26.4) 16.2 (11.5–22.2) 0.0001a
OI (cmH2O per mmHg) 5.3 (2.9–12.4) 7 (3–14.5) 6.7 (4.1–12.3) 7 (5–12.3) 6.6 (2.9–12.3) 0.3
PaO2/FiO2 (mmHg) 235 (144–388) 210 (117–402) 285 (154–412) 333 (196–440) 243 (164–467) 0.0009b
PaCO2 (mmHg) 36 (31–54) 41 (28–63) 42 (31–66) 45 (32–60) 43 (28–52) 0.08
Cardiac index (l min-1 m-2) 4.6 (2.5–6.3) 4.5 (2.5–6.9) 4.3 (2–6.8) 4.7 (2.4–6.2) 5.1 (2.1–6.3) 0.08
LVSWI (g m m-2) 45 (22–71) 43 (22–60) 40 (14–60) 36 (15–58) 42 (14–66) 0.13
MAP (mmHg) 79 (74–103) 81 (69–99) 74 (69–97) 74 (66–93) 73 (69–96) 0.24
PAOP (mmHg) 16 (10–19) 17 (8–22) 17 (11–23) 18 (12–26) 14 (11–23) 0.22
CVP (mmHg) 14 (9–17) 15 (7–19) 15 (9–24) 15 (10–19) 12 (8–18) 0.27
CO2 gap (mmHg) 19 (2–30) 19 (0–40) 18 (0–39) 17 (4–39) 19 (9–39) 0.18
  1. Results are presented as median (range). CVP, central venous pressure; CO2 gap, arterial partial pressure of CO2 [pCO2] minus gastric pCO2; FiO2, fraction of inspired oxygen; LVSWI, left ventricular stroke work index; MAP, mean arterial pressure; OI, oxygenation index, defined as mean airway pressure × FiO2 × 100/arterial pCO2; PaO2, partial pressure of O2; PaCO2, partial pressure of CO2; PAOP, pulmonary arterial occlusion pressure; PEEP, positive end-expiratory pressure. aP < 0.05 for all comparisons except baseline versus PEEP 10 and PEEP 10 versus ideal PEEP. bP < 0.05 for all comparisons except baseline versus PEEP 10, baseline versus PEEP 15, baseline versus ideal PEEP, and PEEP 15 versus ideal PEEP.