Science review: Searching for gene candidates in acute lung injury

Table 1 Biological processes identified by MAPPFinder based on gene expression

GOID	GO Name	Number of changed genes	Number of measured genes	Number of genes in GO	Percentage changed genes	Percentage present genes	Z score
7596	Blood coagulation	8	26	74	30.77	35.14	3.56
6954	Inflammatory response	13	44	168	29.55	26.19	4.35
8285	Negative regulation of cell proliferation	8	32	129	25.00	24.81	2.88
6935	Chemotaxis	7	31	107	22.58	28.97	2.28
6955	Immune response	13	61	569	21.31	10.72	4.17

The bioprocesses affected by mechanical stretch were identified using MAPPFinder [12] software, designed by the BayGenomics PGA group for dynamic linkage of gene expression data to the Gene Ontology (GO; http://www.geneontology.org hierarchy. Data were filtered by number of changed genes (> 5) and Z score (> 2.0) and sorted by percentage changed genes.

ISSN: 1364-8535