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Table 6 Recovery results for patients who became eligible to start the extubation process within 5 days of the start of the study drug infusion

From: Safety and efficacy of analgesia-based sedation with remifentanil versus standard hypnotic-based regimens in intensive care unit patients with brain injuries: a randomised, controlled trial [ISRCTN50308308]

Parameter Remifentanil (n = 47) Fentanyl (n = 22) Morphine (n = 28)
Median time on mechanical ventilation during the treatment period, h (range) 24.83 (12.5–110.2) 24.08 (16.4–70.0) 37.04 (17.8–98.2)
   Hazard ratio relative to comparator   1.21 0.71
   95% CI   0.70, 2.10 0.43, 1.18
   P   0.500 0.188
Median time from the start of the extubation process until actual extubation, h (range) 1.00 (0.0–97.2) 0.68 (0.0–5.6) 1.93 (0.0–96.2)
   Hazard ratio relative to comparator   1.23 0.42
   95% CI   0.70, 2.13 0.25, 0.71
   P   0.474 0.001
Median time from the start of extubation process until ICU discharge, h (range) 43.50 (2.4–150.0) 42.90 (2.2–120.6) 49.63 (3.7–144.2)
   Hazard ratio relative to comparator   1.34 0.98
   95% CI   0.76, 2.37 0.56, 1.70
   P   0.316 0.928
  1. CI, confidence interval; ICU, intensive care unit.