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Table 2 Role of CD18 integrins for neutrophil recruitment in different rodent and rabbit models of acute lung injury

From: Bench-to-bedside review: Acute respiratory distress syndrome – how neutrophils migrate into the lung

CD18 dependency Stimulus
Dependent Escherichia coli
  Pseudomonas aeruginosa
  E. coli endotoxin (intratracheally administered)
  Cobra venom factor
  Hydrochloric acid (contralateral lung)
  IgG immune complex
Independent Streptococcus pneumoniae
  Group B streptococcus
  Staphylococcus aureus
  E. coli endotoxin (systemically administered)
  Hydrochloric acid (site of installation)
  Complement protein C5a
  1. IL, interleukin.