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Table 2 Role of CD18 integrins for neutrophil recruitment in different rodent and rabbit models of acute lung injury

From: Bench-to-bedside review: Acute respiratory distress syndrome – how neutrophils migrate into the lung

CD18 dependency Stimulus
Dependent Escherichia coli
  Pseudomonas aeruginosa
  E. coli endotoxin (intratracheally administered)
  Cobra venom factor
  Hydrochloric acid (contralateral lung)
  IgG immune complex
  IL-1
Independent Streptococcus pneumoniae
  Group B streptococcus
  Staphylococcus aureus
  E. coli endotoxin (systemically administered)
  Hydrochloric acid (site of installation)
  Hyperoxia
  Complement protein C5a
  1. IL, interleukin.