|
Primary adrenal insufficiency
| |
|
Haemorrhage
|
Anticoagulant therapy (heparin, warfarin)
|
|
Cortisol synthesis enzyme inhibition
|
Aminogluthethimide
|
| |
Ketoconazole
|
| |
Fluconazole
|
| |
Etomidate
|
| |
Dexmedetomidine
|
|
Cortisol metabolism activation
|
Phenobarbital
|
| |
Phenytoin
|
| |
Rifampin
|
|
Secondary adrenal insufficiency
| |
|
Suppression of CRH and ACTH synthesis
|
Glucocorticoid therapy (systemic or topical)
|
| |
Megestrol acetate
|
| |
Medroxyprogesterone
|
| |
Ketorolac tromethamine
|
| |
Antidepressant drugs (e.g. imipramine)
|
| |
Opiate drugs
|
|
Peripheral resistance to glucocorticoids
| |
|
Interaction with glucocorticoids receptor
|
Mifepristone
|
|
Inhibition of the glucocorticosteroid-induced gene transcription
|
Antipsychotic drugs (e.g. chlorpromazine)
|
| |
Antidepressant drugs (e.g. imipramine)
|
