Primary adrenal insufficiency
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Haemorrhage
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Anticoagulant therapy (heparin, warfarin)
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Cortisol synthesis enzyme inhibition
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Aminogluthethimide
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Ketoconazole
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Fluconazole
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Etomidate
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Dexmedetomidine
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Cortisol metabolism activation
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Phenobarbital
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Phenytoin
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Rifampin
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Secondary adrenal insufficiency
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Suppression of CRH and ACTH synthesis
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Glucocorticoid therapy (systemic or topical)
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Megestrol acetate
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Medroxyprogesterone
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Ketorolac tromethamine
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Antidepressant drugs (e.g. imipramine)
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Opiate drugs
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Peripheral resistance to glucocorticoids
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Interaction with glucocorticoids receptor
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Mifepristone
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Inhibition of the glucocorticosteroid-induced gene transcription
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Antipsychotic drugs (e.g. chlorpromazine)
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Antidepressant drugs (e.g. imipramine)
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