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Table 2 Regional oxygen-derived variables and portal vein lactate

From: Effects of volume resuscitation on splanchnic perfusion in canine model of severe sepsis induced by live Escherichia coli infusion

Parameter

Baseline

Minutes after bacterial infusion

  

15

90

120

150

Mesenteric DO2 (ml/min)

   Control

71.6 ± 8.5

37.7 ± 3.9*

54.4 ± 9.6*

61.7 ± 10.6

66.6 ± 11.2

   Lactated Ringer's

74.3 ± 9.1

53.5 ± 7.1

37.9 ± 5.2

47.8 ± 4.2

48.2 ± 4.7

Mesenteric O2ER (%)

   Control

15.1 ± 1.8

23.6 ± 3.1*

32.7 ± 3.7*

29.7 ± 4.5*

28.3 ± 3.5*

   Lactated Ringer's

15.6 ± 2.8

19.8 ± 2.6

27.9 ± 2.8

22.3 ± 2.1

24.5 ± 2.3

SpO2 (%)

   Control

88.3 ± 1.6

75.9 ± 3.1*

67.5 ± 3.9*

71.9 ± 4.8*

71.7 ± 3.4*

   Lactated Ringer's

87.9 ± 2.1

80.2 ± 1.9

72.4 ± 3.3

80.5 ± 2.1

77.4 ± 2.2

Portal vein lactate (mmol/l)

   Control

1.56 ± 0.44

1.67 ± 0.37*

3.65 ± 0.32*

3.31 ± 0.35*

3.32 ± 0.28*

   Lactated Ringer's

1.58 ± 0.21

1.88 ± 0.22

3.97 ± 0.54

4.01 ± 0.52

3.55 ± 0.44

Portal–arterial PCO2 gradient (mmHg)

   Control

3.6 ± 1.0

7.9 ± 1.4*

11.1 ± 1.2*

9.3 ± 2.1*

9.6 ± 1.4*

   Lactated Ringer's

4.9 ± 0.9

8.7 ± 1.4

11.1 ± 1.6

6.7 ± 1.7

7.5 ± 1.2

  1. Measurements were taken in control animals (n = 13) and animals treated with lactated Ringer's solution (n = 14). Data are expressed as mean ± standard error of the mean. DO2, oxygen delivery; O2ER, oxygen extraction ratio; PCO2, carbon dioxide tension; SpO2, portal vein oxygen saturation. *P < 0.05, control versus baseline; P < 0.05 lactated Ringer's versus baseline.