Characteristics and outcome for admissions to adult, general critical care units with acute severe asthma: a secondary analysis of the ICNARC Case Mix Programme Database

Table 5 Multiple logistic regression model of patient factors in relation to receipt of mechanical ventilation in the first 24 hours after admission to the Case Mix Programme unit

	Adjusted OR (95% CI)
Patient factor^a	Before adjustment for APACHE II score (n = 1795)^b	After adjustment for APACHE II score (n = 1656)^c
Age (10 years)	1.12 (1.05–1.19)	1.05 (0.96–1.14)
Steroid treatment in previous 6 months	1.00 (0.73–1.38)	0.82 (0.57–1.17)
CPR within 24 hours prior to admission	4.09 (2.10–7.97)	3.65 (1.81–7.36)
Neurological insult in first 24 hours	12.45 (5.65–27.46)	10.75 (4.23–27.31)
Highest heart rate (10 beats/min)	1.00 (0.95–1.06)	0.94 (0.88–1.00)
Lowest PaO₂ (5 kPa)	0.82 (0.72–0.92)	0.80 (0.70–0.92)
pH from ABG with lowest PaO₂ (pH 0.1)	1.00 (0.99–1.00)	1.00 (0.99–1.00)
PaCO₂ from ABG with lowest pH (5 kPa)	5.72 (4.46–7.34)	5.22 (4.02–6.77)
APACHE II score (1 point)	-^d	1.05 (1.02–1.08)

^aReported odds ratio is for an increase (indicated in parentheses) in the associated continuous factor. ^bExcluding admissions who were readmissions to intensive care unit within the same hospital stay, admissions whose ultimate hospital discharge status was missing and admissions for whom any of the entered risk factors were missing. ^cExcluding (in addition to exclusions described in footnote b) admissions not eligible for Acute Physiology and Chronic Health Evaluation (APACHE) II score. ^dFactor not entered into the multiple logistic regression model. ABG, arterial blood gas; CI, confidence interval; CPR, cardiopulmonary resuscitation; Paco₂, arterial carbon dioxide tension; Pao₂, arterial oxygen tension.

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