Characteristics and outcome for admissions to adult, general critical care units with acute severe asthma: a secondary analysis of the ICNARC Case Mix Programme Database

Table 2 Univariate analyses of individual patient factors in relation to ultimate hospital mortality

	Deaths	n ^a	%	OR (95% CI)
Age (years)
0–19	7	230	3.0	1.68 (1.54–1.85) per 10 year increase
20–29	10	336	3.0
30–39	7	348	2.0
40–49	28	338	8.3
50–59	35	328	10.7
60+	112	461	24.3
Sex
Female	142	1365	10.4	1.00
Male	57	676	8.4	0.79 (0.57–1.09)
Steroid treatment in previous 6 months
No	175	1755	10.0	1.00
Yes	24	286	8.4	0.83 (0.53–1.29)
CPR within 24 hours before admission
No	123	1861	6.6	1.00
Yes	73	165	44.2	11.21 (7.84–16.03)
Neurological insult in first 24 hours
No	122	1829	6.7	1.00
Yes	77	212	36.3	7.98 (5.09–10.95)
Highest heart rate (beats/min)
<124	57	661	8.6	1.08 (1.01–1.15) per 10 beats/min increase
124–141	63	700	9.0
≥141	73	641	11.4
Highest respiratory rate (breaths/min)
<26	17	492	3.5	1.01 (0.89–1.15) per 5 breaths/min increase
26–33	15	462	3.2
≥33	22	471	4.6
Lowest Pao₂ (kPa)
<9.8	81	585	13.9	0.89 (0.76–1.05) per 5 kPa increase
9.8–12.4	57	618	9.2
≥12.4	52	614	8.5
pH from ABG with lowest Pao₂
<7.32	99	556	17.8	1.62 (1.37–1.91) per pH 0.1 increase
7.32–7.41	51	656	7.8
≥7.41	40	603	6.6
Paco₂ from ABG with lowest pH (kPa)
<5.7	22	573	3.8	1.62 (1.37–1.91) per 5 kPa increase
5.7–8.2	62	567	10.9
≥8.2	97	586	16.5
Acute Physiology Score
0–8	19	65	2.9	1.18 (1.15–1.21) per 1 point increase
9–12	48	590	8.1
13+	114	567	20.1
APACHE II score
0–10	10	594	1.7	1.18 (1.15–1.21) per 1 point increase
11–15	38	593	6.4
16+	133	621	21.4

^aExcluding admissions who were readmissions to intensive care unit (ICU) within the same hospital stay, admissions whose ultimate hospital discharge status was missing, and admissions missing the specific factor. APACHE, Acute Physiology and Chronic Health Evaluation; CI, confidence interval; CPR, cardiopulmonary resuscitation; OR, odds ratio; Paco₂, arterial carbon dioxide tension; Pao₂, arterial oxygen tension.

ISSN: 1364-8535