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Table

From: Pharmacokinetics of meropenem in intensive care patients receiving continuous renal replacement therapy

Patient

1

2

3

4

5

6

7

8

9

10

Replacement

CVVH

    

CVVHDF

    

Rates (1/h)

1

1.5

2

2

2

1:1

1:1

1:1

1.5:1.5

1.5:1.5

Ctrough (mg/1)

13.3

4.2

3.4

7.2

14.6

13.3

2.5

6.3

0.5

10.8

Cpeak(mg/l)

90.1

127.7

85.2

73.2

81.7

116.3

101.2

115.0

63.1

55.3

C480mins (mg/l)

19.4

10.5

14.3

11.6

23.3

20.5

6.2

18.7

5.7

7.5