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Table 2 Disadvantages of leukoreduction

From: To filter blood or universal leukoreduction: what is the answer?

Cost $600 million/year in USA
  In Rhode Island, prestorage leukoreduction implementation cost $1,466,250 (extrapolating to $319 million across the whole of the USA)
Logistics 2% loss of red blood cells
  Platelet loss of 11% due to trapping