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Table 2 Erythropoiesis during autologous blood donation

From: Autologous blood donation

  Blood removed (donated) Blood produced  
Patients (n) Baseline RBCs (ml) Requested/donated units RBCs (ml) RBCs (ml) Expansion (%) Iron therapy Reference
'Standard phlebotomy'        
   108 1884 3/2.7 522 351 19% po [6]
   22 1936 3/2.8 590 220 11% None [7]
   45 1991 3/2.9 621 331 17% po [7]
   41 1918 3/2.9 603 315 16% po + iv [7]
'Aggressive phlebotomy'        
   30 2075 ≥ 3/3.0 540 397 19% None [8]
   30 2024 ≥ 3/3.1 558 473 23% po [8]
   30 2057 ≥ 3/2.9 522 436 21% iv [8]
   24 2157 6/4.1 683 568 26% po [9,10]
   23 2257 6/4.6 757 440 19% po [11]
  1. Values are expressed as means. iv, intravenous; po, oral; RBC, red blood cell. Data from Goodnough and coworkers [5].