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Table 2 Erythropoiesis during autologous blood donation

From: Autologous blood donation

 

Blood removed (donated)

Blood produced

 

Patients (n)

Baseline RBCs (ml)

Requested/donated units

RBCs (ml)

RBCs (ml)

Expansion (%)

Iron therapy

Reference

'Standard phlebotomy'

       

   108

1884

3/2.7

522

351

19%

po

[6]

   22

1936

3/2.8

590

220

11%

None

[7]

   45

1991

3/2.9

621

331

17%

po

[7]

   41

1918

3/2.9

603

315

16%

po + iv

[7]

'Aggressive phlebotomy'

       

   30

2075

≥ 3/3.0

540

397

19%

None

[8]

   30

2024

≥ 3/3.1

558

473

23%

po

[8]

   30

2057

≥ 3/2.9

522

436

21%

iv

[8]

   24

2157

6/4.1

683

568

26%

po

[9,10]

   23

2257

6/4.6

757

440

19%

po

[11]

  1. Values are expressed as means. iv, intravenous; po, oral; RBC, red blood cell. Data from Goodnough and coworkers [5].