Skip to main content

Table 2 Remifentanil and propofol doses at the time of scheduled down-titrations

From: Offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment

 

Remifentanil infusion rate at start of SDT (μg/kg per hour)

Mean propofol infusion rate at start of SDT (mg/kg per hour)

Number (%) of patients receiving propofol at SDT

Time of SDT

Normal/mild

Moderate/severe

Normal/mild

Moderate/severe

Normal/mild

Moderate/severe

8 hours

8.8 (2.8)

7.0 (3.5)

0.8 (0.1)

0.7 (0.4)

5 (50)

11 (37)

24 hours

9.7 (3.0)

7.5 (3.6)

1.3 (0.9)

1.1 (0.5)

7 (70)

8 (27)

48 hours

10.1 (3.9)

7.6 (2.7)

1.0 (0.6)

0.9 (0.6)

5 (50)

2 (7)

72 hours

9.7 (6.0)

7.7 (2.9)

1.2 (0.7)

0.8 (0.4)

4 (40)

4 (13)

  1. Values are expressed as mean (standard deviation). SDT, scheduled down-titration.