Skip to main content
Figure 1 | Critical Care

Figure 1

From: Offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment

Figure 1

Mean (± 95% confidence interval) time to offset of the pharmacodynamic effects of remifentanil at 8, 24, 48 and 72 hour scheduled down-titrations (SDTs), analyzed using the Cox proportional hazards model. (a) Group with normal/mild renal impairment. Numbers included at each assessment were as follows: 10 at the 8 hour SDT, 10 at the 24 hour SDT, eight at the 48 hour SDT, and six at the 72 hour SDT. (b)Group with moderate/severe renal impairment. Numbers included at each assessment were as follows: 28 at the 8 hour SDT, 25 at the 24 hour SDT, 15 at the 48 hour SDT, and 15 at the 72 hour SDT. P values are as follows (all versus group with normal/mildly impaired renal function): 0.616 at the 8 hour SDT, 0.031 at the 24 hour SDT, 0.998 at the 48 hour SDT, and 0.042 at the 72 hour SDT.

Back to article page

Critical Care

ISSN: 1364-8535