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Table 6 Haemodynamic parameters during the study period (safety population)

From: Remifentanil versus fentanyl for analgesia based sedation to provide patient comfort in the intensive care unit: a randomized, double-blind controlled trial [ISRCTN43755713]

  Remifentanil (n = 115) Fentanyl (n = 81)
Mean arterial pressure   
   Overall weighted mean MAP (mmHg; range) 80.9 (38–128) 79.6 (54–104)
   % of time in which MAP was within 10% of mean baseline value (range) 43.1 (0–100) 48.7 (4–91)
   Number of patients with MAP ≤ 50 mmHg 19 (17%) 8 (10%)
   Number of patients with MAP ≥ 100 mmHg 81 (70%) 52 (64%)
Heart rate   
   Overall weighted mean HR (beats/min; range) 88.3 (63–117) 88.6 (59–129)
   % of time in which HR was within 10% of mean baseline value (range) 54.4 (0–100) 55.6 (5–100)
   Number of patients with HR ≤ 50 beats/min 2 (2%) 3 (4%)
   Number of patients with HR ≥ 120 beats/min 35 (30%) 28 (35%)
  1. The statistical significance of the differences between groups for the mean percentages of time with heart rate (HR) and mean arterial pressure (MAP) within 10% of baseline was not tested. There were no statistically significant differences between groups for any of the other parameters.