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Figure 4 | Critical Care

Figure 4

From: Insulin-like growth factor-1 protects ischemic murine myocardium from ischemia/reperfusion associated injury

Figure 4

Determination of mitochondrial DNA (mtDNA) : nuclear DNA (nDNA) ratio. The mtDNA : nDNA ratio was determined for the following conditions: control; ischemia without reperfusion; modified Kreb's Henseleit working solution (MK) alone for 1 hour; MK alone for 2 hours; MK plus insulin-like growth factor (IGF)-1 for 1 hour; and MK with insulin-like growth factor (IGF)-1 for 2 hours. The number within each histogram represents the number of hearts processed for that condition. The values for mtDNA : nDNA ratio in the controls, ischemic myocardial tissue, and either reperfusion group (MK or IGF-1) were significantly different from each other (P < 0.05).

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