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Table 3 Recommended antihypertensive agents for hypertensive crises

From: Clinical review: The management of hypertensive crises

Condition

Preferred antihypertensive agent

Acute pulmonary edema

Fenoldopam or nitroprusside in combination with nitroglycerin (up to 60 μg/min) and a loop diuretic

Acute myocardial ischemia

Labetalol or esmolol in combination with nitroglycerin (up to 60 μg/min)

Hypertensive encephalopathy

Labetalol, nicardipine, or fenoldopam

Acute aortic dissection

Labetalol or combination of nicardipine or fenoldopam and esmolol or combination of nitroprusside with either esmolol or intravenous metoprolol

Eclampsia

Labetalol or nicardipine. Hydralazine may be used in a non-ICU setting

Acute renal failure/microangiopathic anemia

Fenoldopam or nicardipine

Sympathetic crisis/cocaine overdose

Verapamil, diltiazem, or nicardipine in combination with a benzodiazepine

  1. ICU, intensive care unit.