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Table 3 Recommended antihypertensive agents for hypertensive crises

From: Clinical review: The management of hypertensive crises

Condition Preferred antihypertensive agent
Acute pulmonary edema Fenoldopam or nitroprusside in combination with nitroglycerin (up to 60 μg/min) and a loop diuretic
Acute myocardial ischemia Labetalol or esmolol in combination with nitroglycerin (up to 60 μg/min)
Hypertensive encephalopathy Labetalol, nicardipine, or fenoldopam
Acute aortic dissection Labetalol or combination of nicardipine or fenoldopam and esmolol or combination of nitroprusside with either esmolol or intravenous metoprolol
Eclampsia Labetalol or nicardipine. Hydralazine may be used in a non-ICU setting
Acute renal failure/microangiopathic anemia Fenoldopam or nicardipine
Sympathetic crisis/cocaine overdose Verapamil, diltiazem, or nicardipine in combination with a benzodiazepine
  1. ICU, intensive care unit.