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Table 1 Arteriolar diameters (% alteration)

From: Metformin treatment improves vascular function in rats with neonatal streptozotocin-induced type 2 diabetes

Rats Norepinephrine (4.7 pmol) Norepinephrine (14.1 pmol) Acetylcholine (24 nmol) Sodium nitroprusside (58 nmol) Bradykinin (42 pmol) Histamine (4.1 nmol) Platelet activating factor (60 pmol)
Control 1.41 ± 0.46 7.25 ± 0.98 5.70 ± 0.60 6.16 ± 0.51 6.82 ± 0.29 6.14 ± 0.4 6.88 ± 0.7
  (n = 12) (n = 12) (n = 13) (n = 7) (n = 12) (n = 14) (n = 8)
Diabetic 4.07 ± 0.53 69.29 ± 11.34* 1.17 ± 0.50 2.57 ± 0.68* 1.51 ± 0.23* 2.1 ± 0.37 2.25 ± 0.66*
  (n = 11) (n = 13) (n = 8) (n = 7) (n = 14) (n = 8) (n = 8)
Diabetic + metformin 6.05 ± 0.91 14.89 ± 3.33 1.91 ± 0.82 5.39 ± 0.56 6.88 ± 0.56 7.9 ± 0.71†‡ 5.7 ± 0.9
  (n = 9) (n = 11) (n = 10) (n = 7) (n = 14) (n = 10) (n = 8)
  1. *P < 0.05 in comparison with control rats and diabetic + metformin rats. P < 0.05 in comparison with control rats. P < 0.05 in comparison with diabetic rats.