|
Rats
|
Norepinephrine (4.7 pmol)
|
Norepinephrine (14.1 pmol)
|
Acetylcholine (24 nmol)
|
Sodium nitroprusside (58 nmol)
|
Bradykinin (42 pmol)
|
Histamine (4.1 nmol)
|
Platelet activating factor (60 pmol)
|
|---|
|
Control
|
1.41 ± 0.46
|
7.25 ± 0.98
|
5.70 ± 0.60
|
6.16 ± 0.51
|
6.82 ± 0.29
|
6.14 ± 0.4
|
6.88 ± 0.7
|
| |
(n = 12)
|
(n = 12)
|
(n = 13)
|
(n = 7)
|
(n = 12)
|
(n = 14)
|
(n = 8)
|
|
Diabetic
|
4.07 ± 0.53†
|
69.29 ± 11.34*
|
1.17 ± 0.50†
|
2.57 ± 0.68*
|
1.51 ± 0.23*
|
2.1 ± 0.37†
|
2.25 ± 0.66*
|
| |
(n = 11)
|
(n = 13)
|
(n = 8)
|
(n = 7)
|
(n = 14)
|
(n = 8)
|
(n = 8)
|
|
Diabetic + metformin
|
6.05 ± 0.91†
|
14.89 ± 3.33
|
1.91 ± 0.82†
|
5.39 ± 0.56
|
6.88 ± 0.56
|
7.9 ± 0.71†‡
|
5.7 ± 0.9
|
| |
(n = 9)
|
(n = 11)
|
(n = 10)
|
(n = 7)
|
(n = 14)
|
(n = 10)
|
(n = 8)
|
- *P < 0.05 in comparison with control rats and diabetic + metformin rats. †P < 0.05 in comparison with control rats. ‡P < 0.05 in comparison with diabetic rats.
