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Table 1

From: Is it possible to use levosimedan to treat cardiovascular dysfunction in septic patients?

 

Baseline*

18 h of treatment#

After 1 h EVO**

After 3 h EVO##

12 h with EVO

24 h with LEVO##

Without LEVO 2 h

Without LEVO 12 h

Without LEVO 24 h

Without LEVO 48 h

CI

1.4

2.8

2.8

3.3

3.2

4.2

3.6

3.6

3.7

4.4

MAP

73

92

78

70

70

66

73

88

79

93

PAOP

22

21

16

21

14

20

20

22

21

22

SVO2

68

75

78

79

75

74

74

75

73

77

VO2

85

90

94

102

111

123

122

119

143

121

Lactate

7.43

5.21

2.55

1.77

1.55

1.77

1.55

1.55

1.54

1.91

  1. Hemodynamic support: * 0.6 μg/kg/min noradrenalin + 20 μg/kg/min dobutamine. # 30 μg/kg/min dobutamine + 5 l Ringer's solution + 500 ml hydroxyethylstarch (HES) (200/0.5). ** 20 μg/kg/min dobutamine + 0.1 μg/kg/min levosimedan (LEVO). ## 0.2 μg/kg/min LEVO + 500 ml HES (200/0.5).
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Critical Care

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