Systemic and regional hemodynamic effects of fluid resuscitation in experimental septic shock

Table 1

	Baseline	T30	T90	T210
Mean arterial pressure (mmHg)
Control	105.9 ± 4.6	93.8 ± 4.6^a	62.8 ± 7.6	79.5 ± 5.9
RL, 16 ml/kg	108.7 ± 4.0	98.0 ± 5.2^a	75.1 ± 7.3	88.9 ± 8.9
RL, 32 ml/kg	107.0 ± 2.9	91.1 ± 3.5^a	89.8 ± 6.1	92.1 ± 3.3
Cardiac index (l/min/m²)
Control	2.92 ± 0.09	1.78 ± 0.18^a	1.39 ± 0.13	1.32 ± 0.06
RL, 16 ml/kg	3.23 ± 0.35	2.30 ± 0.34^a	2.40 ± 0.46^b	1.35 ± 0.19
RL, 32 ml/kg	3.10 ± 0.08	1.73 ± 0.18^a	2.68 ± 0.26^b	1.52 ± 0.09
Portal vein flow index (ml/min/m²)
Control	697.8 ± 62.2	390.9 ± 70.6^a	225.2 ± 34.2	183.5 ± 32.3
RL, 16 ml/kg	591.9 ± 41.5	311.6 ± 25.4^a	320.7 ± 47.1^b	201.5 ± 18.9
RL, 32 ml/kg	632.8 ± 25.5	244.5 ± 32.3^a	441.0 ± 59.2^b	162.0 ± 12.4
PCO₂ gap (mmHg)
Control	5.0 ± 2.7	12.6 ± 4,1^a	33.1 ± 4.2	44.3 ± 5.3
RL, 16 ml/kg	2.4 ± 0.9	15.0 ± 4.2^a	22.7 ± 2.3	48.6 ± 3.4
RL, 32 ml/kg	0.6 ± 2.3	6.4 ± 2.8^a	13.8 ± 2.2	35.3 ± 2.5
Arterial lactate (mmol/l)
Control	1.34 ± 0.18	1.53 ± 0.17^a	2.91 ± 0.29	3.33 ± 0.32
RL, 16 ml/kg	1.58 ± 0.17	1.72 ± 0.29	4.23 ± 0.30	5.63 ± 0.37
RL, 32 ml/kg	0.97 ± 0.20	1.77 ± 0.21^a	3.8.7 ± 0.54	2.57 ± 0.40

ISSN: 1364-8535