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Table 2 Parameters measured during titration of positive end-expiratory pressure

From: Gastric intramucosal pH is stable during titration of positive end-expiratory pressure to improve oxygenation in acute respiratory distress syndrome

Parameter

PEEPbaseline

PEEPopt

PEEPmax

P value

PEEP (cmH2O)

5

10.4 ± 3.9

13.3 ± 2.9

0.0001

Ppeak (cmH2O)

27.2 ± 5

31.5 ± 6.2

35 ± 5

0.0001

Pmean (cmH2O)

11.4 ± 1.9

15.9 ± 4.9

19.3 ± 2.8

0.0001

PaO2 (mmHg)

136.6 ± 48.7

231 ± 86.1

226 ± 99.8

0.001

PaCO2 (mmHg)

38.4 ± 7.02

37 ± 7.63

37.4 ± 8.19

0.70

pHi

7.31 ± 0.13

7.32 ± 0.12

7.30 ± 0.12

0.84

P(t-a)CO2 (mmHg)

3.74 ± 8.31

5.27 ± 5.49

7.42 ± 7.39

0.353

CI (l/min per m2)

4.03 ± 1.47

3.72 ± 1.4

3.62 ± 1.21

0.79

CO (l/min)

7.02 ± 2.46

6.61 ± 2.41

6.5 ± 2.15

0.13

MAP (mmHg)

89 ± 17.7

88.4 ± 15.3

83 ± 15.9

0.49

CVP (mmHg)

13 ± 2.9

12 ± 3.4

11.5 ± 2.8

0.45

PCWP (mmHg)

15 ± 3.3

12.7 ± 3.07

12.5 ± 3.1

0.10

DO2 (ml/min per m2)

689 ± 232.9

659.9 ± 221.7

638.5 ± 197.4

0.14

VO2 (ml/min per m2)

244.2 ± 73.4

233 ± 42.08

251.2 ± 49.7

0.84

Qs/Qt (%)

34.41 ± 6.23

23.1 ± 9.18

27.4 ± 6.65

0.03

O2ext (%)

21.88 ± 4.65

27.03 ± 3.22

28.51 ± 8.53

0.57

Cst (ml/cmH2O)

32.3 ± 9.7

33 ± 8.35

32.9 ± 8.5

0.84

  1. CI, cardiac index; CO, cardiac output; Cst, static compliance; CVP, central venous pressure; DO2, oxygen delivery; MAP, mean arterial pressure; O2ext, oxygen extraction ratio; PaO2, partial arterial oxygen tension; PCWP, pulmonary capillary wedge pressure; PEEP, positive end-expiratory pressure; pHi, gastric mucosal pH; Pmean, mean airway pressure; P(t-a)CO2, gap between partial tissue and arterial carbon dioxide tension; Ppeak, peak airway pressure; Qs/Qt, shunt fraction; VO2, oxygen consumption.
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Critical Care

ISSN: 1364-8535