Skip to main content

Table 2 Parameters measured during titration of positive end-expiratory pressure

From: Gastric intramucosal pH is stable during titration of positive end-expiratory pressure to improve oxygenation in acute respiratory distress syndrome

Parameter PEEPbaseline PEEPopt PEEPmax P value
PEEP (cmH2O) 5 10.4 ± 3.9 13.3 ± 2.9 0.0001
Ppeak (cmH2O) 27.2 ± 5 31.5 ± 6.2 35 ± 5 0.0001
Pmean (cmH2O) 11.4 ± 1.9 15.9 ± 4.9 19.3 ± 2.8 0.0001
PaO2 (mmHg) 136.6 ± 48.7 231 ± 86.1 226 ± 99.8 0.001
PaCO2 (mmHg) 38.4 ± 7.02 37 ± 7.63 37.4 ± 8.19 0.70
pHi 7.31 ± 0.13 7.32 ± 0.12 7.30 ± 0.12 0.84
P(t-a)CO2 (mmHg) 3.74 ± 8.31 5.27 ± 5.49 7.42 ± 7.39 0.353
CI (l/min per m2) 4.03 ± 1.47 3.72 ± 1.4 3.62 ± 1.21 0.79
CO (l/min) 7.02 ± 2.46 6.61 ± 2.41 6.5 ± 2.15 0.13
MAP (mmHg) 89 ± 17.7 88.4 ± 15.3 83 ± 15.9 0.49
CVP (mmHg) 13 ± 2.9 12 ± 3.4 11.5 ± 2.8 0.45
PCWP (mmHg) 15 ± 3.3 12.7 ± 3.07 12.5 ± 3.1 0.10
DO2 (ml/min per m2) 689 ± 232.9 659.9 ± 221.7 638.5 ± 197.4 0.14
VO2 (ml/min per m2) 244.2 ± 73.4 233 ± 42.08 251.2 ± 49.7 0.84
Qs/Qt (%) 34.41 ± 6.23 23.1 ± 9.18 27.4 ± 6.65 0.03
O2ext (%) 21.88 ± 4.65 27.03 ± 3.22 28.51 ± 8.53 0.57
Cst (ml/cmH2O) 32.3 ± 9.7 33 ± 8.35 32.9 ± 8.5 0.84
  1. CI, cardiac index; CO, cardiac output; Cst, static compliance; CVP, central venous pressure; DO2, oxygen delivery; MAP, mean arterial pressure; O2ext, oxygen extraction ratio; PaO2, partial arterial oxygen tension; PCWP, pulmonary capillary wedge pressure; PEEP, positive end-expiratory pressure; pHi, gastric mucosal pH; Pmean, mean airway pressure; P(t-a)CO2, gap between partial tissue and arterial carbon dioxide tension; Ppeak, peak airway pressure; Qs/Qt, shunt fraction; VO2, oxygen consumption.