|
Parameter
|
PEEPbaseline
|
PEEPopt
|
PEEPmax
|
P value
|
|---|
|
PEEP (cmH2O)
|
5
|
10.4 ± 3.9
|
13.3 ± 2.9
|
0.0001
|
|
Ppeak (cmH2O)
|
27.2 ± 5
|
31.5 ± 6.2
|
35 ± 5
|
0.0001
|
|
Pmean (cmH2O)
|
11.4 ± 1.9
|
15.9 ± 4.9
|
19.3 ± 2.8
|
0.0001
|
|
PaO2 (mmHg)
|
136.6 ± 48.7
|
231 ± 86.1
|
226 ± 99.8
|
0.001
|
|
PaCO2 (mmHg)
|
38.4 ± 7.02
|
37 ± 7.63
|
37.4 ± 8.19
|
0.70
|
|
pHi
|
7.31 ± 0.13
|
7.32 ± 0.12
|
7.30 ± 0.12
|
0.84
|
|
P(t-a)CO2 (mmHg)
|
3.74 ± 8.31
|
5.27 ± 5.49
|
7.42 ± 7.39
|
0.353
|
|
CI (l/min per m2)
|
4.03 ± 1.47
|
3.72 ± 1.4
|
3.62 ± 1.21
|
0.79
|
|
CO (l/min)
|
7.02 ± 2.46
|
6.61 ± 2.41
|
6.5 ± 2.15
|
0.13
|
|
MAP (mmHg)
|
89 ± 17.7
|
88.4 ± 15.3
|
83 ± 15.9
|
0.49
|
|
CVP (mmHg)
|
13 ± 2.9
|
12 ± 3.4
|
11.5 ± 2.8
|
0.45
|
|
PCWP (mmHg)
|
15 ± 3.3
|
12.7 ± 3.07
|
12.5 ± 3.1
|
0.10
|
|
DO2 (ml/min per m2)
|
689 ± 232.9
|
659.9 ± 221.7
|
638.5 ± 197.4
|
0.14
|
|
VO2 (ml/min per m2)
|
244.2 ± 73.4
|
233 ± 42.08
|
251.2 ± 49.7
|
0.84
|
|
Qs/Qt (%)
|
34.41 ± 6.23
|
23.1 ± 9.18
|
27.4 ± 6.65
|
0.03
|
|
O2ext (%)
|
21.88 ± 4.65
|
27.03 ± 3.22
|
28.51 ± 8.53
|
0.57
|
|
Cst (ml/cmH2O)
|
32.3 ± 9.7
|
33 ± 8.35
|
32.9 ± 8.5
|
0.84
|
- CI, cardiac index; CO, cardiac output; Cst, static compliance; CVP, central venous pressure; DO2, oxygen delivery; MAP, mean arterial pressure; O2ext, oxygen extraction ratio; PaO2, partial arterial oxygen tension; PCWP, pulmonary capillary wedge pressure; PEEP, positive end-expiratory pressure; pHi, gastric mucosal pH; Pmean, mean airway pressure; P(t-a)CO2, gap between partial tissue and arterial carbon dioxide tension; Ppeak, peak airway pressure; Qs/Qt, shunt fraction; VO2, oxygen consumption.
