Table 1
Placebo (n = 11) | Hydrocortisone (n = 11) | P | |
|---|---|---|---|
NF-kκB (1 hour; %) | 66 (27/125) | 75 (50/98) | NS |
NF-kκB (24 hours; %) | 86 (61/116) | 59 (34/105) | NS |
TNF-α (4 hours) | 45 (31/66) | 31 (28/40) | NS |
TNF-α (24 hours) | 41 (17/45) | 27 (16/40) | NS |
IL-6 (pg/ml; 4 hours) | 438 (396/931) | 178 (93/375) | <0.01 |
IL-6 (pg/ml; 24 hours) | 281(245/454) | 139 (104/231) | <0.05 |
IL-10 (pg/ml; 4 hours) | 16 (9/42) | 137 (79/215) | <0.001 |
IL-10 (pg/ml; 24 hours) | 3.5 (2/10) | 3.5 (1/12) | NS |