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Table 1 Gas exchange variables, partial esophageal carbon dioxide tension, and hemodynamic variables during mild and severe hemorrhagic hypotension and following blood reinfusion in anesthetized, spontaneously breathing rats

From: Esophageal capnometry during hemorrhagic shock and after resuscitation in rats

  

Hemorrhage

Blood reinfusion

Variable

Baseline

Mild

Severe

30 min

60 min

PaO2 (torr)

85.4 ± 7.5

105.2 ± 9.6*

116.0 ± 6.3*

90.4 ± 4.2

88.6 ± 7.2

PaCO2 (torr)

38.0 ± 4.8

28.5 ± 4.8*

17.2 ± 3.0*

33.9 ± 4.0

33.1 ± 4.6

PeCO2 (torr)

46.3 ± 6.2

42.8 ± 5.0

36.9 ± 3.0*

39.8 ± 4.3*

41.2 ± 6.8

Base deficit (mmol/l)

-2.9 ± 1.7

-5.5 ± 1.8

-14.4 ± 5.5*

-7.2 ± 4.6*

-7.2 ± 4.0*

pH

7.371 ± 0.05

7.408 ± 0.05

7.340 ± 0.14

7.331 ± 0.09

7.332 ± 0.1

HCO3- (mmol/l)

21.3 ± 1.5

17.3 ± 1.6*

9.2 ± 2.7*

16.9 ± 3.1*

16.9 ± 2.1*

SaO2 (%)

94.0 ± 1.3

97.4 ± 1.2

98.0 ± 1.2

91.3 ± 5.4

91.7 ± 6.0

Hb (g/dl)

14.2 ± 1.0

11.6 ± 1.1*

9.6 ± 1.1*

13.8 ± 0.9

13.7 ± 0.8

MABP (mmHg)

106.4 ± 11.8

71.7 ± 9.6*

50.0 ± 17.1*

96.8 ± 24.6

95.8 ± 24.5

HR (beats/min)

347 ± 16

366 ± 29

447 ± 39*

402 ± 20*

398 ± 22*

  1. Values are expressed as mean ± SD. *P < 0.05, by comparing baseline with other measurements by analysis of variance and Dunnett multiple comparisons test. Hb, hemoglobin; HR, heart rate; MABP, mean arterial blood pressure; PaO2, partial arterial oxygen tension; PaCO2, partial arterial carbon dioxide tension; PeCO2, partial esophageal carbon dioxide tension; SaO2, arterial oxygen saturation.