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Figure 1 | Critical Care

Figure 1

From: Bench-to-bedside review: Functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis

Figure 1

The human Toll-like receptors and their known ligands. CpG, cytosine-phosphoryl-quanine; ECSIT, evolutionarily conserved signaling intermediate of Toll; IκB, inhibitory kappaB; IKK, IκB inducing kinase; IRAK, IL-1 receptor associated kinase; LBP-lipopolysaccharide-binding protein; LPS, lipopolysaccharide; MyD88, myeloid differentiation factor 88; NF-κB, nuclear factor-κ for B cells; NIK, NF-κB inducing kinase; PG, peptidoglycan; TIR, Toll IL-1 receptor domain; TRAF6, Tumor necrosis factor receptor associated factor-6.

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