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Figure 2 | Critical Care

Figure 2

From: Science review: Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: role for hypoxia-inducible factor-1α

Figure 2

Potential oxygen-sensing mechanisms and the role of the transcription factor hypoxia-inducible factor-1 (HIF-1). 6GP, 6-glucose phosphate; 6PG, 6-phosphoglycerate; FAD, flavin adenine dinucleotide oxidized; FADH, flavin adenine dinucleotide reduced; NADP, nicotinamide dinucleotide oxidized; NADPH, nicotinamide dinucleotide reduced; ROS, reactive oxygen species; VHL, von Hippel-Lindau tumor suppressor protein.

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Critical Care

ISSN: 1364-8535