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Figure 2 | Critical Care

Figure 2

From: Science review: Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: role for nuclear factor-κB

Figure 2

A general schematic showing the regulation of cellular processes in response to oxidative stress. Reactive oxygen species may induce cell damage (lung injury) or may initiate a cascade of adaptive signaling mechanisms that ultimately lead to proliferation, differentiation, adaptation or apoptosis. This stands in sharp contrast with the disorderly manner of necrotic, violent death that might be incurred by excessive oxidative stress.

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Critical Care

ISSN: 1364-8535