Figure 3From: Science review: Role of coagulation protease cascades in sepsisTargets of anticoagulant therapy and their efficacy in providing anti-inflammatory benefit in sepsis. Anticoagulants (shown in red and boxed) showed preclinical efficacy in preventing lethality, whereas anticoagulant mechanisms (shown in blue and circled) failed to protect in sepsis. ATIII, antithrombin III; TF, tissue factor; TFPI, tissue factor pathway inhibitor.Back to article page