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Figure 3 | Critical Care

Figure 3

From: Science review: Role of coagulation protease cascades in sepsis

Figure 3

Targets of anticoagulant therapy and their efficacy in providing anti-inflammatory benefit in sepsis. Anticoagulants (shown in red and boxed) showed preclinical efficacy in preventing lethality, whereas anticoagulant mechanisms (shown in blue and circled) failed to protect in sepsis. ATIII, antithrombin III; TF, tissue factor; TFPI, tissue factor pathway inhibitor.

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