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Table 1

From: Complement activation in relation to age in patients with severe sepsis

 

Adult

Elderly

 

Sepsis day 1

Sepsis day 8

Sepsis day 1

Sepsis day 8

C4d (µg/ml)

2.4 (2.0-3.3)

1.7* (3.8-8.3)

3.2 (2.5-7.3)

5.4 (3.9-7.0)

C1-Inh activity (%)

105 (72-132)

148* (128-163)

122 (85-133)

132 (107-156)

C1-Inh protein (%)

136 (107-148)

196* (158-211)

123 (100-154)

147 (120-165)

Bb (µg/ml)

0.55 (0.32-2.74)

0.79 (0.41-1.15)

0.90 (0.68-1.05)

1.03 (0.88-1.25)

C3a (ng/ml)

118 (65-370)

524 (212-689)

204 (102-1129)

372 (187-1154)

  1. *P < 0.05, sepsis day 1 vs sepsis day 8 (Friedman test with post-hoc Wilcoxon).