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Table 2 Indicators of hepatocellular injury and urinary thiobarbituric-acid-reacting substances (TBARS) in preterm infants studied

From: Association of lipid peroxidation with hepatocellular injury in preterm infants

 

Infants

 

Variable

With cholestatis (n = 27)

Controls (n = 16)

P

Direct bilirubin (mg/dl)

3.3 (2.4,7.2)*

1.7 (1.0,1.9)

<0.001

ALT (U/l)

32 (8,127)*

9 (7,16)

0.01

AST (U/l)

71 (40,189)*

33 (22,39)

<0.001

Alkaline phosphatase (U/l)

383 (221,579)

269 (199,450)

0.57

Urinary TBARS (ng/mg creatinine)

2591 (1022,6445)

3368 (1622,4625)

0.93

  1. Values are expressed as medians (25th,75th percentiles). *Significantly different from control group (P < 0.05 using one-way analysis of variance of natural log-transformed variables).