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Table 2 Indicators of hepatocellular injury and urinary thiobarbituric-acid-reacting substances (TBARS) in preterm infants studied

From: Association of lipid peroxidation with hepatocellular injury in preterm infants

  Infants  
Variable With cholestatis (n = 27) Controls (n = 16) P
Direct bilirubin (mg/dl) 3.3 (2.4,7.2)* 1.7 (1.0,1.9) <0.001
ALT (U/l) 32 (8,127)* 9 (7,16) 0.01
AST (U/l) 71 (40,189)* 33 (22,39) <0.001
Alkaline phosphatase (U/l) 383 (221,579) 269 (199,450) 0.57
Urinary TBARS (ng/mg creatinine) 2591 (1022,6445) 3368 (1622,4625) 0.93
  1. Values are expressed as medians (25th,75th percentiles). *Significantly different from control group (P < 0.05 using one-way analysis of variance of natural log-transformed variables).