Table 1 Important studies on hepatic arterial buffer response, with main findings

Lautt (1985) [41]

Cat

Antagonism of HABR by the adenosine antagonist 8-phenyltheophylline

Lautt et al. (1988) [42]

Cat

Hepatic arterial vascular response to intravenous drugs dependent on direct action of the drug on hepatic artery and on indirect effects of drug-induced changes in portal venous blood flow

Lautt and McQuaker (1989) [43]

Cat

Protective dilatation of hepatic artery during haemorrhage is mediated by adenosine

Lautt et al. (1990) [44]

Cat

During high portal venous blood flow, hepatic artery is nearly fully constricted; during low portal venous blood flow, hepatic artery is nearly fully dilated

Henderson et al. (1992) [45]

Human

Intact HABR in liver transplant patients

Ayuse et al. (1994) [46]

Pig

Change in portal venous blood flow alters hepatic arterial resistance upstream from the site of a constant arterial back pressure

Ayuse et al. (1995) [47]

Pig

HABR is abolished during endotoxaemia independently of nitric oxide or α-adrenergic receptor antagonists