Table 3 Average values (means ± SD) of basal cortisol, peak cortisol, cortisol responses to corticotropin, APACHE II and maximum SOFA scores according to survivors and non-survivors in both groups on the first day
From: Physiological-dose steroid therapy in sepsis [ISRCTN36253388]
Steroid therapy group | Standard therapy group | |||||
|---|---|---|---|---|---|---|
Variable | Non-survivors (n = 8) | Survivors (n = 12) | P | Non-survivors (n = 12) | Survivors (n = 8) | P |
Basal cortisol level (μg/dl) | 44.4 ± 24.8 | 52.5 ± 30.5 | 0.536 | 60.5 ± 34.7 | 40.3 ± 19.9 | 0.154 |
Peak cortisol level (μg/dl) | 73.1 ± 35.1 | 79.2 ± 33.5 | 0.699 | 80.7 ± 45.9 | 60.1 ± 25.7 | 0.265 |
Cortisol response (μg/dl) | 28.7 ± 22.1 | 21.2 ± 32.7 | 0.579 | 16.3 ± 24.6 | 18.2 ± 16.3 | 0.835 |
APACHE II score | 17.6 ± 4.5 | 13.8 ± 5.8 | 0.130 | 21 ± 7.9 | 13.3 ± 6 | 0.024 |
Maximum SOFA score | 10.6 ± 3.2 | 5.9 ± 3.3 | 0.009 | 11.4 ± 2.9 | 6 ± 3.3 | 0.003 |