External validation of a modified model of Acute Physiology and Chronic Health Evaluation (APACHE) II for orthotopic liver transplant patients

Table 4 Comparison between the two participating transplant centers

Characteristic	KFNGH	UW	P
Number of patients	63	111
Age (years)	46.25 ± 13.97	51.82 ± 10.12	0.04
Females/males	27/36	43/68	NS
Hepatitis C	36 (57)	10 (9)	<0.001
EtOH	0 (0)	22 (20)	<0.001
HCV-EtOH	2 (3)	23 (21)	0.002
Other etiologies	25 (40)	56 (50)	NS
Actual mortality	6 (9.52)	4 (3.60)	NS
APACHE II score	21.09 ± 5.01	14.37 ± 3.59	<0.001
ROD, original model	20.55 ± 12.94	8.65 ± 4.38	<0.001
ROD, new model	14.54 ± 10.73	5.68 ± 3.01	<0.001
SMR, original model; 95% CI	0.46; 0.17–0.95	0.42; 0.11–1.04
SMR, new model; 95% CI	0.65; 0.25–1.35	0.63; 0.17–1.57

Figures in parentheses are percentages. EtOH, alcohol liver disease; HCV, hepatitis C virus; KFNGH, King Fahad National Guard Hospital; NS, not significant; ROD, risk of death; SMR, standardized mortality ratio; UW, University of Wisconsin.

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