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Table 4 Haemodynamic and respiratory gas modifications at the four time points of the study: subgroups A1 and A2

From: Pruritus: a useful sign for predicting the haemodynamic changes that occur following administration of vancomycin

  

Time point

Parameter

Group

1

2

3

4

HR (beats/min)

A1

58 ± 9

60 ± 10

57 ± 9

55 ± 7

 

A2

65 ± 13

59 ± 13

66 ± 7†

65 ± 6

MSP (mmHg)

A1

89 ± 18

89 ± 19

86 ± 19

88 ± 18

 

A2

76 ± 11

67 ± 16

72 ± 12

78 ± 13

SVRI (dynes·s/cm5 per m2)

A1

2741 ± 635

2578 ± 540

2501 ± 605

2564 ± 447

 

A2

2946 ± 471

2457 ± 482

2080 ± 544*†‡

2554 ± 728

CI (l/min per m2)

A1

2.53 ± 0.5

2.61 ± 0.5

2.61 ± 0.5

2.57 ± 0.4

 

A2

2.00 ± 0.3

2.07 ± 0.5

2.70 ± 0.5*†

2.38 ± 0.4

SVI (ml/beat per m2)

A1

44 ± 5

44 ± 6

46 ± 6

47 ± 7

 

A2

32 ± 9

36 ± 9

41 ± 7*

37 ± 9

PVRI (dynes·s/cm5 per m2)

A1

208 ± 104

207 ± 76

194 ± 77

226 ± 84

 

A2

278 ± 92

256 ± 35

224 ± 36*‡

274 ± 65

PaO2 (mmHg)

A1

83 ± 9

78.2 ± 10

75.3 ± 10

78.9 ± 12

 

A2

76.9 ± 13

68.4 ± 13

65.8 ± 7*

71.4 ± 11

SaO2 (%)

A1

96.2 ± 1

95.3 ± 2

95 ± 2

95.4 ± 2

 

A2

95.1 ± 2

93.6 ± 2

93 ± 2*

94 ± 3

Qsp/Qt (%)

A1

12 ± 4

15 ± 6

15 ± 5

13 ± 6

 

A2

14 ± 6

20 ± 6

20 ± 6*

17 ± 8

  1. *P < 0.05, versus time point 1 within each group. See text for definitions of groups, subgroups and time points. CI, cardiac index; CVP, central venous pressure; HR, heart rate; MPP, mean pulmonary pressure; MSP, mean systemic pressure; PaCO2, arterial carbon dioxide tension; PaO2, arterial oxygen tension; PCWP, pulmonary capillary wedge pressure; PVRI, pulmonary vascular resistance index; Qsp/Qt, shunt fraction; SaO2, arterial oxygen saturation; SVI, stroke volume index; SVRI, systemic vascular resistance index.
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Critical Care

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