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Table 2 Clinical variables seen in the suicidal and accidental overdose groups

From: Acetaminophen toxicity: suicidal vs accidental

Variable Accidental overdose (n = 13) Suicidal overdose (n = 80) P value
Presentation >24 hours after overdose (n/n studied [%]) 6/9 (66) 7/55 (13) < 0.001
Peak acetaminophen (mg/l)    < 0.050
   Mean ± SD 64.5 ± 61.8 121.7 ± 97.0  
   Median 49 99  
   Range 0–184 0–439  
Peak acetaminophen <10 mg/l (n [%]) 5 (38) 8 (10) NS
Peak ALT (IU/l)    0.070
   Mean ± SD 1386 ± 1918 580 ± 1836  
   Median 187 30  
   Range 30–5584 30–10356  
Peak AST (IU/l)    0.070
   Mean ± SD 1330 ± 2697 504 ± 1708  
   Median 114 30  
   Range 30–9794 30–10773  
Peak aminotransferase >1000 IU/l (n [%]) 5 (39) 10 (12) < 0.050
Peak prothrombin time (seconds)    < 0.050
   Mean ± SD 15.6 ± 7.4 12.7 ± 2.1  
   Median 12 12  
   Range 12–35 12–25  
Peak serum bilirubin (mg/dl)    < 0.050
   Mean 3.8 ± 5.5 1.3 ± 1.3  
   Median 1 1  
   Range 1–5 1–10  
N-acetylcysteine therapy (n [%]) 8 (62) 59 (73) 0.500
Hepatic coma (n [%]) 2 (15) 0 (0) < 0.050
Death (n [%]) 2 (15) 0 (0) < 0.050
Length of stay in hospital (days)    < 0.010
   Mean 6.4 ± 6.1 3.9 ± 2.7  
   Median 4 3  
   Range 1–17 1–17