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Table 1 Renal replacement therapy support based on underlying demand and capacity framework

From: Challenges and pitfalls when implementing renal replacement therapy in the ICU

Demand Capacity Example Action
High Normal High catabolic state Reduce demand if possible
   High nutritional loading Monitor for renal support
   Poisoning  
High Low Decreased GFR from AKI Renal support
    Reduce demand if possible
Normal Low CKD Add renal support if necessary to maintain steady state
   Noncatabolic  
   AKI  
Low Low Malnutrition and wasting CKD Assess for nutritional state and add renal support if necessary
  1. AKI acute kidney injury, CKD chronic kidney disease, GFR glomerular filtration rate