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Table 1 Recovery from ICU via Surveillance, Exercise, and Nutrition (RISEN) protocol

From: Winning the war against ICU-acquired weakness: new innovations in nutrition and exercise physiology

Day 1 (ICU admission)
Baseline nutritional and metabolic evaluation
Nutrition risk score (NUTRIC score?)
Metabolic evaluation with indirect calorimetry
Baseline muscle evaluation
Lean body mass ultrasound
Muscle glycogen ultrasound
Markers of muscle injury?
CPK-MM (creatine phosphokinase-muscle component)
Myoglobin
LDH-(lactate dehydrogenase)
Every 3-7 days post ICU admission
Ongoing nutritional evaluation
Indirect calorimetry to guide feeding and assess recovery and mitochondrial function along with lactate measurements.
Muscle evaluation
Lean body mass ultrasound
Muscle glycogen ultrasound
Markers of muscle injury?
CPK-MM
Myoglobin
Physiologic exercise evaluation (when able)
Diagnose exercise/mitochondrial function
Individualized exercise prescription including resistance training to improve metabolic and musculoskeletal function.