Skip to main content
Figure 2 | Critical Care

Figure 2

From: Bench-to-bedside review: Toll-like receptors and their role in septic shock

Figure 2

Comparisons between the signaling pathways in the insect and mammalian IL-1/Toll-like receptor (TLR) pathways. (d), Drosophilia homolog; ECSIT, evolutionarily conserved signaling intermediate of Toll; HSP, heat shock protein; IKB, inhibitory subunit κB; IKK, I-κB kinase; IRAK, IL-1 receptor-associated kinase; LBP, lipopolysaccharide binding protein; LPS, lipopolysaccharide; LTA, lipoteichoic acid; MEKK, mitogen-activated protein extracellular activated receptor kinase kinase; MyD88, myeloid differentiation factor; NF-κB, nuclear factor-κB; TNF, tumor necrosis factor; TRAF6, tumor necrosis factor receptor-associated factor 6.

Back to article page