Table 1 When to contact a specialist liver centre in patients with acetaminophen-induced hepatotoxicity
From: Acetaminophen poisoning: an update for the intensivist
Progressive coagulopathy: PT in seconds greater than the number of hours since ingestion (or if the INR is >2 at 24 h, >4 at 48 h, and >6 at 72 h) |
|---|
Renal impairment (creatinine >200 mol/l) |
Hypoglycaemia |
Metabolic acidosis (pH <7.35) |
Hypotension despite fluid resuscitation |
Encephalopathy |