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Table 5 Initial ventilator settings in status asthmaticus

From: Clinical review: Severe asthma

Setting Recommendation
Mode Pressure-controlled ventilation
Respiratory rate 10–15 breaths/min
Tidal volume 6–10 ml/kg
Minute ventilation 8–10 L/min
PEEP 0 cmH2O
Inspiratory/Expiratory ratio ≥ 1:3
Inspiratory flow ≥ 100 L/min
FIO2 Maintain SaO2 >90%
Pplat <35 cm H2O
VEI <1.4 L
  1. FIO2, fraction of inspired oxygen; PEEP, positive end-expiratory pressure; Pplat, end-inspiratory plateau pressure; SaO2, oxygen saturation; VEI, end-inspired volume above apneic functional residual capacity.